Lipoid bodies in semen: normal and abnormalities
Spermogram is an objective reflection not only of male fertility, but also of the health of a number of organs involved in the formation of seminal fluid.
Erythrocytes, lecithin grains in spermograms are indicators by the value of which the doctor may suspect the presence of inflammatory processes in the reproductive system and prescribe an additional examination of the man in order to identify the pathological focus.
Red blood cells
Red blood cells red blood cells are the main component of the blood component. Their appearance in semen is called hemospermia. This condition does not always indicate the development of the disease: the presence of red blood cells in the ejaculate can be caused by an active sex life (due to rupture of the vessels of the urethra), anticoagulants can also trigger bleeding. In such cases, the blood in the form of scarlet inclusions is usually visible to the naked eye (false hemospermia), the phenomenon quickly passes.
True hemospermia is already more dangerous, since red blood cells do not attach to sperm in the urethra, but along the path of ejaculate: testicles, seminal vesicles, prostate. Severe hemospermia is defined as a brownish hue of seminal fluid, hidden - by semen.
Red blood cells in the sperm are rare, but appear if there is inflammation of the prostate gland or adenoma. Usually the process is accompanied by additional symptoms:
The process of inflammation of the prostate may be accompanied by difficult urination of a man.
- urination is not free enough, requires tension,
- discomfort or lower abdominal pain,
- blood may appear in the urine
- periodic or permanent erectile dysfunction.
In such cases, blood may be released due to pressure on the urethra by an enlarged prostate gland.
Often the admixture of red blood cells in the semen is due to the presence of stones in the prostate, injuring the walls of the ducts. The blood enters the ejaculate when it passes through the prostate gland and mixed with the secretion produced.
In men of retirement age, it is likely that red blood cells in semen are a sign of a malignant tumor of the prostate.
All pathologies related to the prostate gland are mainly diagnosed by TRUS.
Sperm synthesis occurs directly in the testicles, so any deviations in the work of these genitals affect the quality of sperm and seminal fluid composition.
Red blood cells in the ejaculate may be a consequence of epididymitis - inflammation of the epididymis. The cause may be infections of a different nature (herpes, influenza, and mumps). Also provoke a disease capable of prolonged cycling, frequent erections without ejaculation, sexual excesses, injuries, reduced immunity. Inflamed tissues are weakened and destroyed, resulting in the release of red blood cells, mixing with the ejaculate in the appendages.
In addition to blood, in the semen for epididymitis in the acute form, other signs are characteristic:
For epididymitis in acute form, the temperature increases
- temperature rise,
- sharp pains in the scrotum, radiating to the groin, back, abdomen,
- the testicle is enlarged, painful, the skin of the scrotum is red,
- uncomfortable urination,
- suppurations in the area of the appendage, fistulas are likely.
Chronic epididymitis occurs in a milder form: dull periodic pain in the groin, the testicle is not significantly enlarged. This type of disease without treatment threatens with irreversible infertility.
Epididymitis is diagnosed by visual inspection, blood test, ultrasound.
Orchitis is called testicular inflammation, often occurring against the background of epididymitis. The disease is provoked by viruses, injuries, and infections. Sharp pains in the scrotum and fever are characteristic of the acute form of orchitis. At the same time, the skin above the inflamed testicle acquires a bluish color a few hours after the process begins. Red blood cells in semen appear due to the destruction of weakened tissues. Without qualified help, an abscess is possible.
Orchitis is diagnosed visually, by palpation, as well as with the help of a general analysis of urine and blood, ultrasound, bakposeva ejaculate.
The presence of red blood cells semen can show against the background of active inflammation of the seminal vesicles (vesiculitis). Sperm before release passes through the vesicles, mixing with the secret they produce. Inflammation can be triggered by both infections and stagnation of seminal fluid, impaired blood supply. The chronic form is mainly due to urogenital infections.
Symptoms of an acute vesiculitis:
In acute vesiculitis, there may be pain in the pelvic region, aggravated by a full bladder.
- pain in the pelvic region, radiating to the sacrum. Strengthens with a filled bladder,
- fever, weakness,
- painful ejaculation with blood impurities.
The chronic form of the disease proceeds without temperature, but the discomfort accompanies all sexual intercourses, the quality of the orgasm decreases, the aching pain in the sacrum area is characteristic.
Rectal examination, ultrasound, vesiculography, CT scan, urinalysis, semen analysis are used for the diagnosis.
Colliculitis is an inflammation of the seed tubercle - a small elevation on the back wall, passing through the prostate of the urethra. The appearance of red blood cells in the sperm may indicate the development of this disease. In addition to blood cells, semen also has the following symptoms:
- dull pain in the groin,
- discomfort in the high part of the urethra after ejaculation,
- priapism (painful erection),
- involuntary ejaculation during bowel movements (rarely, but only with colliculitis),
- early ejaculation, low sperm discharge,
- possible blood in the urine
- frequent wet dreams.
An informative diagnostic method is urethroscopy.
The more lecithin kernels in prostate juice, the better it functions.
Lecithin granules (or lipoid bodies) are part of the prostatic juice, a set of essential phospholipids produced by the prostate. Their presence in the spermogram is justified, since the sperm passes through the ducts of the prostate gland, enriching it with juice, entraining lecithin grains.
Lipoid bodies produce prostate epithelium. In the semen should be a lot, given that in 1 ml of prostatic secretion normally contains more than 10 million grains. They give the ejaculate a white color. The more grains in the juice of the prostate, the better it functions.
Causes and consequences of the lack of lecithin grains
If the spermogram shows insufficient lipid bodies (limited number or absence), then there is reason to suspect prostate gland disease.
Accurately diagnose the presence of abnormalities in the work of the prostate can be directly analyzed prostate secretion. The study draws attention to the ratio of leukocytes and lipoid cells. In the presence of an inflammatory process, leukocytes predominate, but not always their source is the prostate: the cause may be a disease of the urethra, seminal vesicles. But the reverse is also possible, in which prostatitis is obvious, but there are no leukocytes. This is possible with focal inflammation and obliteration (blockage) of part of the prostatic ducts.
The secret of the prostate is usually collected from the urethra by rectal stimulation of the prostate gland, but puncture sampling can be performed.
If there are no lipoid bodies in prostate juice, this may mean the following:
- The material is not collected correctly
- irregular or insufficient stimulation of the prostate during the intake of juice,
- inflammation of the prostate has led to the overlap of the ducts with clots of leukocytes, stagnation of the ejaculate.
In addition to lipoid bodies, prostate juice contains:
If there are no lipoid bodies in the prostate juice, it may be that the material is not collected correctly.
- red blood cells
- white blood cells (rate from 8 to 10 in the field of view under a microscope),
- amyloid bodies,
- epithelial cells.
The epithelial cell count is also present in the spermogram. Their origin can be from both the urethra and the prostate. In normal prostatic cells, there must be a minimum number. If there are a lot of them, then this indicates an inflammatory process in the organ (chronic prostatitis).
The effect of chronic prostatitis on the quality of sperm
Chronic prostatitis, in which the spermogram shows a critically small amount of lecithin grains, affects not only the male urinary system, but also its reproductive function. This is expressed in a decrease in libido, erectile dysfunction, deterioration of sperm quality.
Lecithin granules affect the contractile function of the prostate, are the nutrient medium of sperm. Their lack is fraught with impaired motility of germ cells. Even if, against the background of a small number of grains, sperm motility is within the normal range, they are fast-exhausted and insufficiently active in relation to the egg cell. Therefore, even with good remaining semen readings, a lack of lecithin grains can lead to problems with conception, although it is not a determining factor.
In addition to reducing mobility, sperm on the background of prostatitis can also decrease their number, viability, and with a long course of the disease, it is likely that morphological indicators will deteriorate. The cause is the products of infectious-inflammatory intoxication - inflammatory mediators. Pathological microorganisms that provoke inflammation of the prostate tend to stimulate the production of antisperm antibodies. Chlamydia and E. coli can be attached to sperm.
Male sex cells are damaged by active forms of oxygen, which are produced against the background of bacterial prostatitis.
As a result, the number of lecithin grains in the spermogram may be the key to uncovering the causes of the conception problem in a natural way, although some doctors underestimate this indicator, considering that its value does not directly affect the fertilization process.
The erythrocytes and lecithin grains in the spermogram reflect the health status of the male reproductive system, but if there are deviations of quantitative values from the norm, one should not panic before the diagnosis. The indicators can change from time to time, therefore, for reliable results, the spermogram is performed several times with a certain time interval. If the values are stably beyond the norm, then additional studies are assigned.
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This analysis is of great importance for the identification of pathologies of the male genitourinary system. Poor performance is not an absolute sterility sentence. Currently, there are many methods that allow a couple to conceive a child. Consider the main indicators that matter when deciphering the analysis:
- Volume A meager amount of sperm may indicate the presence of a pathological process that reduces the chances of conception. But It is worth noting that a small amount of ejaculate due to the frequent intimate life before the analysis. That is why sexual abstinence is strongly recommended for four days prior to the delivery of material for research.
- Consistency. This parameter involves the determination of sperm viscosity. This is an important indicator, because excessive density of the material may impede the process of conception.
- Liquefaction time. Normally, the ejaculate liquefies between 15 minutes and 1 hour.
- Acidity. Normal values are considered pH values above 7.2.
- Concentration of sperm. For successful conception, an amount of more than 20 million per milliliter is needed.
- The total number of sperm. The greater their amount in seminal fluid, the better.
- Mobility. In this indicator, spermatozoa of category A and category B are isolated. The latter move much more slowly. Normally, it is necessary to have at least 25% of category A spermatozoa. Also, to confirm male normal fertility, the sum of sperm cells A and B should be equal to 50%. Two other categories are not considered in this case.
- Morphology by Kruger. This indicator allows you to select defective sperm.
- Cell viability. Normally, there must be at least half of the live sperm in seminal fluid.
- Macrophages. An increase in their number in semen may indicate the presence of an infection.
- Leukocytes. Normally, no more than a million white blood cells are present in 1 milliliter of ejaculate.
- Agglutination (bonding). Normally, glued sperm should not be, as they are considered defective and are not able to participate in conception.
- Amyloid bodies, which should not be detected in the material taken.
- Lipoid bodies, which are an essential component of sperm. We will tell about them in more detail.
To answer the question of how long sperm are alive, you need to have an understanding of how they are produced. Their production begins in the testicles, after which they are transferred to the appendages, where maturation occurs. Then full-fledged sperm cells are located at the entrance to the seed channel. Older inactive male cells are removed by spermatophages (special white blood cells). Sperm is updated every three months.
On average, it takes about 2 months for the spermatozoon to grow, matured and able to fertilize the egg. Then within a month he waits for ejaculation, after which he dies. If ejaculation has occurred, the viability of the spermatozoon will depend on whether it goes to the external environment (stays alive for a few minutes) or into the vagina (it can be viable for several days). It is worth noting that when it enters the female body, the spermatozoa that carry the Y chromosomes live on average for a day.
Also on the viability of the sperm is influenced by external factors. How long a sperm cell lives also depends on the ambient temperature, the use of lubricants, and the administration of medications.
Semen Preparation Rules
To identify the most accurate result of the examination, it is necessary to follow a number of rules, since the sperm components are very sensitive to the effects of external factors. Consider the recommended rules before passing the analysis:
- Sex abstinence for 3-4 days.
- The need to give up smoking, alcohol, fatty foods, spicy foods and caffeine 4 days before the analysis.
- For several days you can not use drugs. If this is not possible, you must notify the technician.
- It is forbidden to visit saunas, baths, solariums and take a hot bath before analysis.
Repeated semen research is recommended in the same laboratory as the previous one, in compliance with all the above rules. This is due to the fact that the method of analysis and the equipment used may differ in different laboratories. The question of how much spermogram costs is decided directly at the clinic, since the analysis depends on a number of factors. On average, the service will cost 2-2.5 thousand rubles.
Lipoid bodies, which may also be called lecithin grains, are non-cellular formations of a rounded or angular form. Have the ability to refract light by microscopic examination. Lipoid bodies in moderation must be constantly present in the ejaculate. Their absence or a significant decrease indicates the development of the pathological process in the body of a man. This is due to the fact that lecithin grains enter the semen with the juice of the prostate gland, which explains their mandatory presence in the ejaculate.
Lipoid bodies consist of the following components:
- Phospholipids. They are contained in all cells of the body and are composed of acids and alcohols. Participate in the restoration of cells after any damage, maintain their structure and ensure the flexibility of cell membranes.
- Higher fatty acids, divided into unsaturated and saturated.
- Vitamin B4 (choline). He is involved in the protection of cells from various damage. This substance can be synthesized in the body independently, but people engaged in physical labor and sports should additionally use foods and vitamin complexes containing choline. It is important to note that vitamin B4 increases the activity of male germ cells, and in old age can prevent prostate gland dysfunction.
Functions of lipoid bodies
Currently, experts identify the following functions that perform lecithin grain:
- They are a breeding ground for sperm.
- Promote the activity of male germ cells.
- Оказывают влияние на сократительную функцию предстательной железы.
- Уменьшают риск развития фиброза простаты.
The exact number of lecithin grains in the normal spermogram is not determined. When decoding the results, it is necessary to evaluate a set of indicators. Currently, it is considered normal value of 5-10 million per 1 ml of sperm.
But It is worth noting that there are still disputes among specialists regarding the impact of the amount of these inclusions on the normal spermogram. There have been cases when, with a reduced amount of lecithin grains, but the normal values of other ejaculate indicators, the male fertile function was normal.
Causes of lack of lecithin grain
The absence or insufficient number of lipoid bodies can be caused by the following factors:
- Wrong sampling of material for research.
- Inflammatory processes in the prostate gland.
- Improper stimulation of the gland before taking the material.
- Sperm stagnation.
- The presence of stones in the prostate.
- Obstruction of the tubules.
It happens that with prolonged abstinence there is a large number of lipoid cells. An increase in choline in the body can lead to the release of toxic substances that can cause dangerous pathologies and the destruction of spermatozoa.
It is important to note that the negative effect that lipoid bodies can have is compensated for by other components contained in semen. For example, spermine prevents the damaging effects of choline on germ cells.
Of the large number of diseases, which may indicate a decrease in the number of lipoid cells in the semen, the most common are the following:
- Prostatitis in acute or chronic form. Often, this pathology is a consequence of colds or infections. An acute form of the disease is indicated by a decrease in lipid bodies and an increase in leukocytes. Frequent urination and pain in the groin may disturb. If lecithin grains are completely absent, then we can talk about the development of chronic prostatitis, which can form infertility or impotence.
- Prostate adenoma. Hormonal disorders can lead to the development of this disease. Pathology develops slowly. In the early stages there are practically no noticeable symptoms. When this disease is very important timely diagnosis and treatment started on time.
- Oncological processes occurring in the prostate gland. The reasons for their development have not yet been fully identified. It is supposed that neglected pathologies of the prostate gland (for example, adenoma), the age of a man, and also hormonal disorders can contribute to this.
Prevention of prostate diseases
A man at any age is very important to take care of their health.
- Once a year it is recommended to visit a doctor and take spermogram, because many diseases in the early stages of development do not have obvious manifestations, which can lead to the development of complications, which will be quite difficult to cure.
- Need to deal with moderate exercise.
- Fiber must be present in the diet.
- It is necessary to monitor their weight, not allowing obesity.
- In time to treat diseases of the genitourinary system.
This applies not only to men of reproductive age, but also to elderly patients. The timely detection of abnormalities in the spermogram, as well as the treatment started on time, give a positive prognosis in most cases.
If the analysis revealed a pathological change in the number of lipoid cells in the ejaculate, the doctor sends the patient to additional tests to identify the causes of this condition. After that, an effective treatment is prescribed. It is not recommended to try to independently decipher the values of spermograms and self-medicate, as you can only aggravate the situation If re-delivery of material for research is required, it is recommended to use the services of the same laboratory as the previous time. About how much semen in a particular laboratory, should be checked with the administrator.
Normally, lecithin grains are found in the secret of the genital glands. They are white blotches. These components are not counted when performing semen, just as a result of their presence. For what scientists present in the semen lecithin bodies are unknown. It is believed that if they are not in the semen, then the man may suffer from infertility, but to establish an accurate diagnosis, it is necessary to pay attention to other indicators of semen.
At the same time, if a man is sexually active, the number of these components of sperm decreases. This observation is based on the assumption that the number of lecithin kernels will increase when sperm stagnates. There are cases when men with a high content of lecithin grains and almost normal sperm analysis turned out to be fruitless.
Lecithin granules are formed by phospholipids, choline, higher fatty acids. These elements are becoming popular in the construction of lipid membranes. Thanks to them, the sperm can penetrate the egg without damaging its membrane. Choline is nothing but vitamin B4. The body can replenish its amount by breaking up lecithin.
Choline affects the body not only in this way. But its content in the body should not exceed a certain amount. Otherwise, during its decomposition many toxic substances are formed. The lack of lecithin in the body is never formed, as it comes from the outside with food.
The most valuable source of lecithin is chicken eggs. With their frequent use increases the risk of prostate cancer. Therefore, doctors recommend to men to eat no more than four eggs a week.
Several years ago, scientists conducted special studies, the purpose of which was to establish the influence of lecithin grains on semen. As a result, we managed to find out that when lecithin grains are destroyed, choline is released, which accumulates in the tissues of the prostate gland and can provoke the formation of a cancerous tumor. In addition, choline has a negative effect on sperm.
Disputes about the role of lecithin seeds in sperm are ongoing. Doctors could not come to a consensus. Someone believes that their influence on the male sex cells is destructive, others believe that without their presence, the chances of fertilizing the egg are significantly reduced. Significant funds for the study of this problem were not allocated, and the efforts of enthusiasts were not enough. Lipoid bodies in spermogram normally completely cover the entire field of view, therefore they immediately attract attention.
The negative effect of lecithin is compensated and balanced by other components of the sperm. Residual bodies in the semen also normally should not be present. They are formed in the process of sperm formation or in the destruction of defective sperm. The presence of these elements in semen is evidence that sperm maturation is not as it should be.
A large number of these elements indicates an inflammatory process in the testicles and appendages. Lipoid bodies in small quantities can be a sign that an inflammatory process is brewing in the prostate. The complete absence of lipoid cells may indicate the presence of tumors in the prostate. The same signs appear when the ducts are blocked.
Amyloid bodies in spermogram are normal, as opposed to lipoid, should not be detected. If they are present there, there is an inflammatory process in the prostate gland. Amyloid bodies are formed as a result of the breakdown of the epithelium in glandular vesicles, and are found in men over 50 years of age.
If you smell the semen, you can feel its sour smell. This sperm gives sperm. This substance is part of the sperm for the sole purpose - to maintain its alkaline reaction. Spermine and substances like it that make up sperm stabilize sperm DNA. They are necessary for spermatozoa to maintain their vitality. They also act as advocates of prostate gland cells from the adverse effects of lecithin.
The prostate gland also synthesizes citric acid. She is necessarily present in the semen. Acid is necessary for the normal synthesis of certain enzymes. These enzymes in turn make the sperm more viscous, and the sperm more mobile. A decrease in the content of these enzymes and a decrease or absence of lecithin grains is an indicator of a decrease in prostate function. These two indicators allow you to indirectly judge the state of the prostate. If you conduct research regularly, you can identify prostate disease even at the initial stages.
Delivery of the analysis allows to get an idea of the health of the prostate gland. In addition, the analysis determines whether a man is barren or not. When referring to a doctor, this analysis is assigned first. In the event of an abnormality, the analysis should be given regularly
The spermogram is a basic and very informative research method, which is able at the cellular level to indicate the presence of pathology in a specific area. Excess or failure of any of the indicators indicates a failure in the reproductive systems of men.
The juice of the prostate gland is the main component of the seed. At more than 90%, it consists of water. The rest is enzymes, proteins, salts of certain minerals.
In the prostate secretion, unique non-cellular particles are found - amyloid, lecithin or lipoid bodies, as well as leukocytes and epithelial cells.
Seminal fluid, according to official medical sources, is the secret of the prostate and seminal vesicles, it is a liquid element of sperm.
And only mixing with the spermatozoa formed in the testicles, the seminal fluid is called sperm or ejaculate.
Lipoid substance is present in any person. This is a plural amount of fat and fat-like substances that are contained in every living cell. The second name for lipoid cells is lecithin, which refers to the group of complex lipids. It is noteworthy that lipids serve as progenitors of prostaglandins, which are contained in large quantities in sperm and are so useful in post-term pregnancy.
Lipoid bodies in semen are the absolute norm. They are in large quantities necessarily present in the semen. When conducting analysis, they tightly cover the field of view. Lipoid bodies are the product of prostate gland secretion. It is their presence together with cholesterol crystals, due to the ability to refract light rays, provides the inherent opalescent glow of the ejaculate.
Lipoid bodies in semen are a sign of normal functioning of the prostate. Reducing their number may indicate an inflammatory process of the prostate, and the complete disappearance of the malignancy or blockage of ducts due to the formation of stones.
Other items in semen
If lecithin grains are normally required in sperm of a healthy male, then amyloid bodies, on the contrary, should not be found in the spermogram. Finding them in the ejaculate indicates chronic inflammation and congestion in the prostate gland. These are starch-like, round-shaped particles, which are detected in the analysis by staining the sperm with a special solution. Occur in the glandular vesicles of the prostate as a result of the collapse of dead epithelial cells. In men after 50 years, amyloid bodies are defined more often.
Also found are spermine crystals in spermogram, or Bether crystals. They are formed when the sperm stays in the air or is cooled at the time of evaporation of water from phosphate salts and spermine. It is indicative of the fact that at a low concentration or the complete absence of spermatozoa crystallization occurs much faster.
If residual bodies were found in the spermogram, this means that the process of maturation of the spermatozoon does not take place in an appropriate way. These elements represent the product of the destruction of spermatids with ineffective spermatogenesis and in the period of detachment of the sperm from the capsule. Normally, they should not exceed 2% -10% of the total sperm count. An increase in their number usually indicates inflammation in the testicles and appendages.
To have healthy offspring, to be a “full-fledged man” - the desires that are laid down by nature itself. The ideal system of the human body is able to signal in various ways malfunctions. Therefore, you should pay attention to such an indicator of male health as the quality of sperm. Regular visits to the urologist and control parameters of the seed can significantly improve and extend the reproductive health of the stronger sex.
This medical term refers to specific formations of a round or oval shape, resembling starch. They are formed in the glandular vesicles of the prostate if there is an inflammatory process. By themselves, they are not dangerous and are not pathological, but their presence, as a rule, indicates deviations in the health of the prostate gland.
In the normal spermogram amyloid Taurus should not be.
In the sperm of education fall with the juice of the prostate, therefore, their detection in the ejaculate may indicate:
- chronic prostatitis,
- stagnation of fluid in the prostate, resulting from inflammation, prolonged abstinence, lack of physical activity, injuries,
- adenoma (the appearance of increasing nodules).
If there are many formations, the doctor may suggest the presence of bacterial prostatitis, while the non-bacterial nature of the disease is less. In that case, if both macrophages and multinucleated cells are detected at the same time, we can talk about adenoma.
Spermogram is a very informative diagnostic method, with which you can determine the violation in a specific area as accurately as possible. After all, even small deviations from the norm of absolutely all indicators usually indicate some kind of malfunction in the body.
The main component of the male seminal fluid - the juice of the prostate gland, consisting of water by 90%. All the rest is protein, enzymatic substances, mineral salts.
Also in the prostate secretion are epithelial cells, leukocytes, amyloid and lipoid bodies, also called lecithin grains. All these components are mixed with sperm produced in the testicles, and form the male sperm.
What are the lipoid bodies
The composition of lecithin grains includes the following components:
- saturated and unsaturated fatty acids,
- phospholipids - restore cells to the field of damage, are responsible for the flexibility of cell membranes,
- Choline protects and increases the activity of male sex cells, prevents the development of prostate gland pathologies. Normally, it is synthesized in the body, but with increased physical exertion it becomes necessary to receive choline from the outside (vitamins, diet).
Normal readings in semen
What should be the exact number of lipoid cells in the semen has not yet been determined.
Among experts there are disputes regarding this issue. There are many cases in which the underestimated values of lecithin kernels did not affect the fertility of men (provided that all other indicators are normal).
In this video, the doctor shows the result of the semen and what the semen looks like under a microscope (lipoid bodies are clearly visible):
Lipoid bodies reduce the risk of developing prostate fibrosis and promote the activity of germ cells. They are also a breeding ground for sperm and have a positive effect on the function of the prostate gland.
Excessive content of these particles is observed with prolonged sexual abstinence. This leads to an excess of choline in the body, which is fraught with the development of dangerous diseases.