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Cream and candles Depantol: instructions for use, price, analogues for Medside

Depantol (vaginal suppositories) Rating: 152

Depantol refers to antiseptic and antimicrobial drugs for the treatment of gynecological diseases. It has a regenerating, antiseptic and metabolic effect. It is prescribed for the treatment of acute and chronic vaginitis, cervical erosion, as well as to improve the regeneration of the vaginal mucosa.

Analogues of the drug Depantol

Analogue cheaper from 157 rubles.

Hexicon is a Russian-made drug with antiseptic and antimicrobial action. Used for the prevention of sexually transmitted diseases, infectious and inflammatory complications in obstetrics-gynecology and for the treatment of chronic exo-and endocervicitis, vaginitis.

Analogue cheaper from 269 rubles.

Chlorhexidine is the most beneficial analogue of Hexicon with the same active ingredient in the composition. Indications for use are identical. Effective antiseptic, but often causing allergic reactions, in the form of itching, burning. When these symptoms appear, the use of the drug should be immediately abandoned and consult a doctor.

Analogue cheaper from 150 rubles.

Biochemist (Russia) Chlorhexidine is the most beneficial analogue of Hexicon with the same active ingredient in the composition. Indications for use are identical. Effective antiseptic, but often causing allergic reactions, in the form of itching, burning. When these symptoms appear, the use of the drug should be immediately abandoned and consult a doctor.

Pharmacodynamics and pharmacokinetics

Chlorhexidine, which is part of the drug, has a strong antibacterial action. Depresses livelihoods dermatophytesdifferent fungi and protozoa, bacteria Chlamydia spp., Neisseria gonorrhoeae Bacteroides fragilis, Staphylococcus spp., Treponema pallidum, Ureaplasma spp., Gardnerella vaginalis, Escherichia coli, Streptococcus spp. However, the substance is static or ineffective in the fight against acid-resistant strains bacteria, their spores and strains Pseudomonas spp. and Proteus spp.

Dexpanthenol - vitamin B, entering the body, turns into pantothenic acidwhich takes part in acetylation, metabolic processes (fat and carbohydrate). Substance is involved in the synthesis acetylcholine, glucocorticosteroids,and porphyrins. Also dexpanthenol tends to accelerate mitosis and stimulate the regeneration of mucous membranes.

Both active ingredients of the drug are quite active in the presence of pus, blood and other secrets. Substances penetrate into the systemic circulation in very small quantities.

Indications for use

  • from erosion (with a specific etiology of the disease),
  • acute and chronic vaginitis,
  • at endocervites and exocervites,
  • after cryodestruction, laser destruction, diathermocoagulation (in gynecology).

They can prescribe depantol candles after cauterization of erosion, to improve recovery of the vaginal mucosa and uterus.

Often appoint candles after childbirth, gynecological and obstetric operations.

  • for abrasions, cuts, cracks, bites, burns, scratches, if there is a risk of infection,
  • for treatment eczema, atopic dermatitis and other dermatosis,
  • scratches and abrasions with signs of infection in children,
  • for the treatment of cracks and inflammations of the nipples of the mammary glands in nursing mothers,
  • for treatment of wounds after operations.

Depantol Instructions (Method and Dosage)

Candles Depantol, instructions for use.

Suppositories use intravaginally. First, the candle is released from the packaging and injected deep inside. Adults appoint one candle, twice a day. The course of treatment is usually from a week to 10 days. If necessary, it can be extended to 20 days.

The drug can be used during menstruation, since the active ingredients retain their activity. But it is better to begin treatment at the end of menstruation or immediately after it.

Instructions for ointment.

Outwardly. The cream is applied in accordance with the recommendations of the doctor.

Ointment is applied with a thin layer on the damaged areas, gently rubbing. If necessary, the wound can be treated surgically. Do not apply the drug under occlusive dressing.

Wash your hands well after using the cream.

For children with diaper dermatitis, the drug is applied after bathing and changing clothes.

For breast treatment in lactating women, ointment is rubbed on a nipple after each feeding. Before the next feeding, it is important not to forget to clean the breast well of ointment residues.

Release form and composition

Depantol is available in the following dosage forms:

  • Cream for external use almost white or white in aluminum tubes of 25, 30 or 50 g, in a cardboard bundle one tube.
  • Vaginal suppositories of white color, allowed grayish or yellowish tint and marbling of the surface. Candles have a torpedo shape, packed in blisters of 5 pieces each, in a cardboard bundle of 1 or 2 blisters.

The preparation contains such active ingredients as dexpanthenol (0.1 g and 0.0525 g in one suppository and 1 g of cream, respectively) and chlorhexidine digluconate (0.016 g and 0.00802 g in one candle and 1 g of cream, respectively).

Auxiliary components of suppositories - macrogol 1500 (98-92%) and macrogol 400 (2-8%), cream - liquid paraffin, petrolatum, macrogol cetostearate, propylene glycol, sodium hydrogen phosphate dodecahydrate, cetostearyl alcohol, potassium dihydrogen phosphate and purified water.

Pharmacological effect

Depantol is a combined agent used for topical administration, with antimicrobial, regenerating, and metabolic effects.

  1. Chlorhexidine is active against Gram-negative and Gram-positive microorganisms: Chlamydia spp., Treponema pallidum, Neisseria gonorrhoeae, Ureaplasma spp., Bacteroides fragilis, Gardnerella vaginalis, Staphylococcus spp., Streptococcus, in-affine systems, in-affine systems, in-affine systems, in the affinity system, in starchiches, pills, gardnerella vaginalis, Staphylococcus spp. Individual strains of Proteus spp., Pseudomonas spp., Bacterial spores and acid-resistant forms of bacteria are not sensitive to chlorhexidine.
  2. Dexpanthenol, which is part of the preparation, activates the regeneration of mucous membranes, stabilizes cell metabolism, increases the rate of mitosis and the strength of collagen fibers.

The drug does not affect the functional activity of lactobacilli. In the presence of pus and blood retains activity.

Use during pregnancy and lactation

Specialists from the field of gynecology, say that the use of candles Depantol during the period of gestation, can only be under the careful supervision of a specialist. In the presence of hypersensitivity to the composition of the drug and the threat of premature onset of labor should abandon the use of the drug.

During lactation, the use of the drug is allowed. Strain the milk or stop breastfeeding completely, is not required.

Instructions for use

The instructions for use indicated that Depantol used intravaginally. Before use, the suppository should be removed from the contour packaging.

Introduce 1 suppository 2 times / day for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days.

How to enter a candle correctly?

Conventional hygiene procedures should be carried out prior to insertion into the vagina of the suppository. It is most convenient to introduce Depanthol with supine legs bent at the knees. Having relaxed the abdominal muscles, you should hold the candle as far as possible inside, as otherwise it may fall out.

After that, you need to lie down for 15-20 minutes. It is necessary that Depanthol began to dissolve inside. So the probability of prolapse of the suppository is significantly reduced.

Drug interaction

Depantol is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose) and soaps, if they are administered intravaginally.

We picked up some reviews of women about the drug Depantol:

  1. Julia . There were excretions, in principle, tolerable (habitual), but unpleasant ... After the second candle, there was a noticeable improvement ... After 3 days I go to the gynecologist, I hope for better health - not only excretions, but also erosion)))
  2. Veronica. Depantol super candles, exactly what you need after childbirth, is checked on your own skin)) If there are stitches or, God forbid, tears, Depanthol will greatly ease the condition and speed healing, it is 100%. But only you do not tune in advance for all sorts of horrors)) think positively that everything will be fine, no breaks and other things, in general, do not force up ahead of time. Easy delivery and healthy baby!
  3. Lika. After excision w / m, the doctor prescribed Depantol. Having read reviews, about a sidewalk ... itch, etc., of course, it was with caution the first use. But I excluded soap, right after reading in the instruction on incompatibility, and for 4 days I take 2 capsules a day - never itching and burning was not. At the moment, the most uncomfortable - this is what flow strongly. The consistency of water. But all is solved with gaskets.
  4. Karina. I put such vaginal suppositories for the sake of reliable prophylaxis after every holiday rest. I am afraid that the infection will not bring home as a souvenir. Home procedure does not take much time, does not cause much discomfort. Candles put for 10 days on 1 suppository in the vagina at night. It really helps me, and quickly.

Medical officers note that today they are increasingly prescribing Depantole in gynecological practice. Doctors claim its high efficacy and rapid therapeutic effect. Even in severe cases, the maximum course of treatment lasted no more than 14 days. The main importance of the drug is in the postpartum activity and the treatment of erosion.

Although there is no exact combination of active ingredients (dexpanthenol + chlorhexidine), but according to pharmacological characteristics, a number of drugs can replace it. For convenience, we divide them by active ingredients.

And so, Depantol candles analogues:

These drugs basically contain the substance Povidone-Iodine. Indications for use are similar to Depantol: vaginal infections in the acute and chronic stages, trichomoniasis, prevention of infection in gynecological operations.

Before using analogues consult your doctor.


Currently, pharmaceutical companies offer various products in the form of ointments or creams containing dexpanthenol. They are appointed to improve the regenerative abilities of tissues. Dexpanthenol ointment, as well as Depantol cream, is used as an external remedy in the treatment of inflammatory processes of the skin: dermatitis, trophic ulcers, boils. The drug is indicated after mechanical damage, surgical interventions. It can be applied to scratches, areas in the place of bedsores.

Like Depantol Cream, the cheaper drug Dexpanthenol can be used to treat nipples with a tendency to crack for breastfeeding women. The ointment can be used to treat the skin of children prone to diaper dermatitis, as well as after exposure to sunlight.

The tool should be applied to the damaged surface of the skin only after its treatment with a disinfecting solution! The drug Depantol, as well as analog Dexpanthenol, must be used for young children, after washing the skin with warm water and replacing underwear.

Dexpanthenol is cheaper than Depantol and ranges from 127 rubles.

Candles Livarol have antimycotic action due to its constituent ketoconazole. This component suppresses various types of fungal infection found in the vagina, the cervix. The drug can be used not only for acute or chronic candidiasis, but also in the presence of several types of pathogenic pathogens. Livarol is recommended to be used for impaired genital microflora.

Candles are prescribed not only for treatment, but also for prophylactic purposes, especially after treatment with antibacterial drugs. Experts advise the use of this drug to women who have had an infectious disease, which has reduced the body's defenses.

The advantage of candles with ketoconazole is the lack of impact on other organs and systems. The drug is well tolerated by women. Allergic reactions to the components are extremely rare.

If you compare the cost, then the drug Depantol is a bit cheaper than the analogue Livarol. Price of candles with ketoconazole is about 480 rubles.

Osarbon, as well as Depantol candles, is manufactured by Nizhpharm (Russia). Analogue much cheaper than the original. Suppositories contain acetarsol, which blocks the enzymatic system of fungi. Thanks to boric acid, which is part of the vagina and the cervix, an acidic medium is maintained that prevents the negative effects on the body of acetarsol.

Osarbon is prescribed for the complex treatment of bacterial colpitis. The drug has a number of contraindications:

  • pregnancy,
  • lactation period
  • liver dysfunction, kidneys,
  • hemorrhagic diathesis,
  • diabetes.

If a woman bought Osarbon suppositories, but they led to the development of dermatitis or hyperthermia, a cheaper drug should be replaced with a more suitable counterpart. In some cases, candles with acetarsol can cause hepatitis and polyneuritis. If there are signs of a violation of the liver, it is necessary to stop using this medication. Osarbon is available in pharmacies by prescription only.

The analogue is cheaper than the drug Depantol. It can be purchased for 130 rubles.

Chlorhexidine candles

Chlorhexidine suppositories have a pronounced antiseptic effect, inhibit the reproduction of certain types of viruses, bacteria and fungi. The advantage of a cheaper drug is the lack of activity against lactic acid bacteria. The main substance has no pronounced effect on the body's systems, which allows the use of candles in the presence of chronic diseases.

Chlorhexidine suppositories, which are analogous to Depantol suppositories, are prescribed for the prevention of sexually transmitted infections, bacterial infection during labor, and surgical interventions on the neck. The drug is used for bacterial vaginosis and mixed-type colpitis. The active components of the candle act even in the presence of purulent fluid and blood in the vagina and cervix.

Chlorhexidine is undesirable to use in the period of treatment with iodine-containing agents intended for intravaginal therapy. The drug is usually well tolerated by patients. Itching and irritation of the cervical mucosa, vagina is rare.

Candles with chlorhexidine during pregnancy are used exclusively for the purpose of the gynecologist!

The cost of suppositories in pharmacies is 130 rubles, which is cheaper than Depantol.


Preparations in the form of candles for vaginal use are prescribed by a doctor after a full examination of patients. Not all remedies of this type are allowed to be used during pregnancy and lactation. Do not continue treatment with vaginal suppositories, including cheap analogues of Depantol, if in the cervix, the vagina appears itchy, irritated. Visit a doctor and use it to choose a more suitable drug!

For the treatment and prevention of back and joint diseases, our readers use the rapidly growing and non-surgical treatment method, which is gaining popularity, recommended by leading orthopedic surgeons. After carefully reading it, we decided to offer it to your attention.

For the treatment and prevention of back and joint diseases, our readers use the rapidly growing and non-surgical treatment method, which is gaining popularity, recommended by leading orthopedic surgeons. After carefully reading it, we decided to offer it to your attention.


Contraindications to the use of the drug is hypersensitivity to the components of the cream. The manual contains information about possible adverse reactions of a local nature. Redness, itching and burning in the places of application of the cream were rarely observed. "Depantol" is applied until complete restoration of damaged skin. If the condition worsens, swelling and inflammation become more pronounced, you should contact your dermatologist.

How to find a cheap equivalent of expensive medicine?

To find an inexpensive analogue of a drug, a generic or a synonym, first of all we recommend to pay attention to the composition, namely to the same active ingredients and indications for use. The active ingredients of the drug are the same and will indicate that the drug is synonymous with a drug that is pharmaceutically equivalent or a pharmaceutical alternative. However, do not forget about the inactive components of similar drugs that may affect safety and efficacy. Do not forget about the advice of doctors, self-treatment can harm your health, so always consult a doctor before using any medicine.

Depantol instruction

Composition and release form
1 g of cream contains D-panthenol (dexpanthenol) - 52.5 mg, chlorhexidine digluconate - 8.02 mg
Excipients: propylene glycol, macrogol-20-cetostearate, cetostearyl alcohol, medical vaseline oil (liquid paraffin), petrolatum (soft paraffin), sodium hydrogen phosphate dodecahydrate, potassium dihydrogen phosphate, purified water - up to 1 g
on 25, 30 or 50 g in tubes, in a cardboard pack.

Pharmacological properties
Depantol is a combined preparation for local use, providing a regenerating, antiseptic, metabolic effect.

Dexpanthenol is a vitamin B group, is metabolized in the body to pantothenic acid, which is an integral part of coenzyme A and is involved in acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, glucocorticosteroids, porphyrins, stimulates skin regeneration, normalizes cellular metabolism, accelerates mitosis. strength of collagen fibers. It has a regenerating, vitamin, metabolic and anti-inflammatory effect.
Chlorhexidine - an antimicrobial drug, is an antiseptic. Effective against gram-positive and gram-negative bacteria, including Staphylococcus spp., Enterococcus spp., Pseudomonas aeruginosa, E.coli, Streptococcus spp., As well as yeast-like fungi and dermatophytes. Remains active in the presence of blood, pus, various secrets and organic matter.

Depantol cream protects the wound surface from infections, suppresses the course of the infection process and accelerates healing.

Indications for use
Treatment and prevention of infected skin lesions:

  • for treating wounds at the risk of infection (abrasions, cuts, scratches, cracks, scratches - including after insect bites, burns, trophic ulcers),
  • for the treatment of postoperative wounds,
  • for the treatment of infected wounds, burns (including sunburns), bedsores, abrasions, cuts, cracks, trophic ulcers, diaper rash,
  • for the treatment of infected dermatoses (including eczema and atopic dermatitis).

In children, it is also used for diaper dermatitis, scratches with signs of infection.
In nursing mothers - with cracks and inflammation of the nipples of the mammary glands with signs of infection.

Individual intolerance to the components of the drug.

Dosage and administration
Outwardly. Depantol cream is applied with a thin layer to the affected skin area 1 or several times a day according to indications.

Breastfeeding mothers lubricate the infected surface of the nipple with a cream after breastfeeding.
Infants are applied to the site of infection after a change of linen or water treatment.

Side effect
Allergic reactions are possible.

Interaction with other drugs
Chlorhexidine is not compatible with soap and other anionic substances.

special instructions
Avoid eye contact.
In pregnancy and lactation, use should be avoided over large areas.

Storage conditions
Keep out of the reach of children at a temperature not exceeding 25 ° C.

Drug properties

Depantol is a combination of two active substances. Dexpanthenol is vitamin B5, which in the body turns into calcium pantothenate during metabolic processes. The element acts as part of acetylation coenzymes, promotes carbohydrate metabolism, synthesizes neurotransmitters that perform neuromuscular transmission. The substance produces corticosteroids and tetrapirrol porphine compounds, thereby accelerating the indirect division of cells, strengthens collagen bonds, improves regeneration. Dexpanthenol has a pronounced anti-inflammatory and restorative property.

Hlorgiksedin is a derivative of biguanide (hypoglycemic substance). It interacts with phosphate chains, from which the membrane of bacteria becomes thin and permeable. Violation of the integrity of the shells leads to the death of pathogens. The element is active against the following gram-positive and negative strains:

  • Trichomonas
  • Tripony
  • Gonococci
  • Chlamydia
  • Ureaplasma
  • Bacteroids
  • Gardnerella
  • Streptococcus
  • Staphylococcus
  • Pseudomonadas
  • Enterococci
  • Esherechies if
  • Dermatophytes
  • Herpes virus
  • Yeast-like protozoa.

Tuberculosis bacteria are resistant. The drug is stable, remains active for several hours with external use. Partially reduces, but does not stop activity in the presence of exudate.

The cream protects damage to the epidermis from repeated infections, quickly heals wounds and suppresses the functions of pathogens. The drug contains no fats, which allows free access of oxygen to the tissues. Absorption into the blood is insignificant.

Release Categories

Average price: 250 rub

Depanthol goes on sale in the form of a milky-white cream, packaged in tubes of aluminum alloy 30 mg each. Polypropylene white cover and protective foil membrane, which is opened by the reverse side of the cap. The cardboard box of a pale blue tint with a blue-green stripe and a stylized image of a chamomile includes instruction and 1 tube. The cream has a light pleasant smell, well applied, does not stain, quickly absorbed.

Ways and rules of application

The cream is applied with a thin film on the affected area, give time for absorption, you can rub a little, if the nature of damage permits .. It is not recommended to use the composition for compresses. After the mixture is absorbed, the wound is tied with a sterile gauze double-layer tape, if it is necessary to close it from the access of air. Before use, the affected area should be cleared of exudate. Assign to treat the epidermis 1-2 times a day. If your hands do not have scratches, bites or burns and do not require treatment, they should be washed after the procedure.

Newborns are smeared with diaper rash and rash after bathing and each change of the diaper.

Women suffering from cracked nipples while nursing a baby, apply the cream after lactation. Before you apply the baby to the breast, the mammary glands must be cleaned with running water.

Storage rules

The composition is valid for 3 years. Keep it in a cool dark place away from children.

There are a number of drugs designed to heal infected areas of the skin, the action of which is identical to the properties of Depantol:

Roche, Switzerland.
Cost: Cream 5% 30 gm - 400-450 rubles, ointment 100 gm - 700-780 rubles.

The drug has a regenerating, moisturizing and anti-inflammatory effect. The main active substance - dexpantenol stimulates metabolic processes, increases the strength of collagen structures, restores the surface of the skin and mucous membranes. The drug is rapidly absorbed by the epidermis, forming a pantothenic oxidant, which is one of the components of coenzyme compounds.

The cream is designed to heal minor wounds, eliminate diaper rash and pressure sores. Suitable for the treatment of thermal and chemical burns, insect bites. The tool is used for erosive lesions of the genital system.

Available in two forms. Light milk cream, homogeneous, without foreign inclusions. It has a specific faint odor. Ointment opaque, plastic, pale yellow hue smells of lanolin. It is packaged in aluminum tubes with a plastic cap and metallized protection. Open the back of the cap. The box is katonny, white-blue with a logo of the company. The package includes instruction and 1 tube.


  • Quickly heals scratches and abrasions
  • Suitable for children.


  • High price
  • Not suitable for the treatment of infected wounds.

Gideon Richter, Hungary
Cost: Gel 15 um - 350-400 rubles.

Antimicrobial agent that promotes accelerated tissue regeneration. Contains zinc hyaluronate, carbomer, sodium hydroxide. Designed to eliminate acne thiopacteria. As a result of the infection, the permeability of the sebaceous glands is reduced, the components of the product eliminate the stagnation and the deficiency of hyaluronic acid in the affected areas. Increases the activity of macrophages and white blood elements, stimulates the antiseptic properties of the substance.

The gel is intended for the treatment of acne of various etiologies, papulesis, trophic wounds, fistulas, burns and cuts. The composition quickly cleans the skin, fills the wounds with the elements necessary for recovery. It is a protective barrier to re-infection.

Available in tubes in the form of a transparent pale yellow liniment. The plastic cap is provided with a perforating tip, which pierces the protective film before use. The box is cardboard, white, with a blue-orange stripe. The package includes a tube with a similar pattern and instructions.


  • Compatible with other drugs.
  • Quickly restores cover.


  • May cause an allergic reaction.
  • Banned during pregnancy.

Ratiopharm, Germany
Cost: 6% cream 30 ml - 100-130 rubles, spray 150 ml - 300-350 rubles.

The product contains dexpanthenol, stimulates the healing of epithelial tissue. Promotes accelerated cell regeneration. The drug strengthens collagen fibers, improves metabolism. By interacting with the skin, it provides a deficit of pantonen, which is necessary to eliminate wounds. Quickly absorbed, binds to protein elements at the cellular level.

Designed to treat skin ulcers, thermal burns, chemical damage, scratches, dermatitis, bedsores. It helps with diaper rash, is used as a cosmetic product protecting it from weather conditions: wind, frost, ultraviolet radiation, precipitation.

Available in the form of a cream or foam mass. The first type is packaged in polypropylene tubes with a lid, equipped with a perforating tip. The second option is a spray that, when extruded, forms a porous light mixture in an aluminum bottle with a spray cap. The composition has a white tint, has a slight specific smell. Cardboard box. With an orange pattern or inscription and a stylized image of flames. Package includes 1 tube or bottle and instructions.


  • Appointed to process and accelerate wound healing.
  • Quickly relieves pain and inflammation.


  • Not suitable for repairing infected areas.
  • May cause allergies.